Importantly, the loss of HFSC markers such as CD34 cannot be taken as proof that the stem cell niche is irreversibly damaged. Even at 5 months, hardly any CD34+ HFSCs were detected in EGFR ΔEgr2 mice.

BEAM-101, a gene-editing stem cell therapy, showed early signs of efficacy among the first treated sickle cell patients in a ...

Single-cell analysis of CML patients bone marrow at diagnosis reveals coexistence of CD26-CD35+ healthy stem cells and CD26+CD35- CML stem cells, and how the ratio between these impacts TKI response.

RCCS San Raffaele Scientific Institute in Milan researchers have discovered that hematopoietic stem cells (HSCs) adapt their lineage commitment during gene therapy based on the underlying genetic ...

in pre- and post-hematopoietic stem cell (HSC) transplant. Dr. Leen has been with BCM’s CAGT since 2002, is the senior or co-author on more than 100 publications, is a named inventor on 14 published ...

Skeletal stem cells have been isolated from various tissues, including periosteum and bone marrow, where they exhibit key functions in bone biology and hematopoiesis, respectively. The role of ...

In a recent article, researchers explored how single-layer graphene oxide (slGO) nanosheets enhance bone marrow stem cell ...

Half of donors back out when informed they are a match. Here's one writer's personal account of donating—and why she'd do it ...

A team of researchers at Broad Institute of MIT and Harvard, in a long-term project that has included industry collaborators ...

Even though stem cell donation rates are abysmally low across Canada, particularly in Quebec, doctors were able to find ...

Increased production of cholesterol by stem cells in the brain contributes to neurological damage in multiple sclerosis, a ...

Researchers have uncovered a key protein process that controls the activation of dormant brain stem cells, essential for ...