Cell division, the basic means by which genetic information is passed from generation to generation, involves tightly coordinated movements of a cell's DNA. This page describes the major phases of ...

During the first part of anaphase, the kinetochore microtubules shorten, and the chromosomes move toward the spindle poles. During the second part of anaphase, the spindle poles separate as the ...

The membrane around the nucleus disappears. Metaphase Chromosomes and their copies line up in the middle of the cell. Anaphase Chromosomes and their copies are pulled to different ends of the cell.

A study in Nature Communications shows how scientists can control cell division on demand outside of a living system. The ...

My research focuses on the segregation of chromosomes during cell division. Chromosomes are the bodies that contain our DNA and it’s critical that each cell has the correct DNA in the correct quantity ...

In the 1980s, scientists knew little about the X and Y chromosomes. What they did understand was that every cell in the body contains 23 pairs of chromosomes. Each of these pairs is similar ...

anaphase, and telophase. See Table 1 for a review of genetic terminology. During oogenesis and spermatogenesis, each parent contributes 23 chromosomes to the zygote through a process of ...

The mitotic checkpoint (MC) ensures proper segregation of chromosomes by delaying anaphase until all kinetochores are bound to microtubules. This inhibitory signal is composed of a complex containing ...

Chromosome transmission errors may also sensitize tumor cells ... For instance, acute inhibition of Plk1 at anaphase onset revealed its essential requirement for targeting the RhoGEF Ect2 to the ...

Looking at the cytoskeleton spindle fiber (microtubules spanning the length of the cell not attached to chromosomes), how might these structures affect the cell structure – as a preview of anaphase?