Cell division, the basic means by which genetic information is passed from generation to generation, involves tightly coordinated movements of a cell's DNA. This page describes the major phases of ...

A complex checkpoint mechanism determines whether the spindle is properly assembled, and for the most part, only cells with correctly assembled spindles enter anaphase. The progression of cells ...

Nucleosomes were most constrained when chromosomes were being moved to opposite poles of the cell during anaphase, a specific ...

Metaphase Chromosomes and their copies line up in the middle of the cell. Anaphase Chromosomes and their copies are pulled to different ends of the cell. Telophase New membranes form around the ...

Exquisite insight into chromosome separation reveals the intricate relationships between molecular changes and large-scale ...

The density reaches a maximum in late mitosis (anaphase), when mitotic chromosomes are most condensed. A team of scientists studying cell division developed a special light microscopy system and ...

RPE-1 cells adapt to aneuploidy in vitro, a process characterized by reduced CIN and inflammation. This study shows that this ...

My research focuses on the segregation of chromosomes during cell division. Chromosomes are the bodies that contain our DNA and it’s critical that each cell has the correct DNA in the correct quantity ...

The discovery of a molecular process that slows down cell division could provide new understanding about how some cancers develop. J. Maciejowski, H. Dreschler, K ...

This is effected by the Anaphase Promoting Complex/Cyclosome (APC/C) ubiquitin ligase that is regulated by the Spindle Assembly Checkpoint (SAC). The SAC prevents the APC/C from recognising Cyclin B1, ...